1,3-O-Isopropylidene Simvastatin Dimer Impurity

• Catalog No.: I871150
• M. F.: C53H80O10
• M. W.: 877.1963

SYNONYMS

• IUPAC name: (1S,3R,7S,8S,8aR)-8-{2-[(4R,6R)-6-(2-{[(2R,4R)-2-{2-[(1S,2S,6R,8S,8aR)-8-[(2,2-dimethylbutanoyl)oxy]-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]ethyl}-6-oxooxan-4-yl]oxy}-2-oxoethyl)-2,2-dimethyl-1,3-dioxan-4-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate
• IUPAC Traditional name: (1S,3R,7S,8S,8aR)-8-{2-[(4R,6R)-6-(2-{[(2R,4R)-2-{2-[(1S,2S,6R,8S,8aR)-8-[(2,2-dimethylbutanoyl)oxy]-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]ethyl}-6-oxooxan-4-yl]oxy}-2-oxoethyl)-2,2-dimethyl-1,3-dioxan-4-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate

PROPERTIES

• Solubility: Chloroform
• Solubility: Dichloromethane
• Solubility: Ethyl Acetate

DETAILS

Description (English)

An impurity of Simvastatin (Dimer).

REFERENCES

• Wang, L., et al.: J. Pharm. Biomed. Anal., 21, 1243 (2000)
• Srinivasu, M., et al.: J. Pharm. Biomed. Anal., 29, 715 (2000)
• Vuletic, M., et al.: J. Pharm. Biomed. Anal., 37, 715 (2000)