Irinotecan-d10 Hydrochloride

• Catalog No.: I767502
• M. F.: C33H39ClN4O6
• M. W.: 623.13896
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0^2,^1^1.0^4,^9.0^1^5,^2^0]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-7-yl 4-[(^2H₁₀)piperidin-1-yl]piperidine-1-carboxylate hydrochloride
• IUPAC Traditional name: (19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0^2,^1^1.0^4,^9.0^1^5,^2^0]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-7-yl 4-[(^2H₁₀)piperidin-1-yl]piperidine-1-carboxylate hydrochloride
• Synonyms: [1,4’-Bipiperidine]-1’-carboxylic Acid (4S)-4,11-Diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3’,4’:6,7]indolizino[1,2-b]quinolin-9-yl Ester Hydrochloride

PROPERTIES

• Apperance: Yellow Solid
• Melting Point: >200°C (dec.)
• Solubility: DMSO
• Solubility: Methanol
• Solubility: Water
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

Deuterated Irinotecan, a DNA topoisomerase inhibitor.

REFERENCES

• Kunimoto, T., et al.: Cancer Res., 47, 5944 (1987)
• Shimada, Y., et al.: J. Clin. Oncol., 11, 909 (1993)