IPI-926 Hydrochloride

• Catalog No.: I739300
• CAS Number: 1169829-40-6
• M. F.: C29H49ClN2O3S
• M. W.: 541.22896

SYNONYMS

• IUPAC name: N-[(3'R,3'aS,4aR,6'S,6aR,6bS,7'aR,9S,12aS,12bS)-3',6',11,12b-tetramethyl-2,3,3'a,4,4',4a,5,5',6,6',6a,6b,7,7',7'a,8,10,12,12a,12b-icosahydro-1H,3'H-spiro[azuleno[2,1-a]naphthalene-9,2'-furo[3,2-b]pyridine]-3-yl]methanesulfonamide hydrochloride
• IUPAC Traditional name: N-[(3'R,3'aS,4aR,6'S,6aR,6bS,7'aR,9S,12aS,12bS)-3',6',11,12b-tetramethyl-1,2,3,3'a,4,4',4a,5,5',6,6',6a,6b,7,7',7'a,8,10,12,12a-icosahydro-3'H-spiro[azuleno[2,1-a]naphthalene-9,2'-furo[3,2-b]pyridine]-3-yl]methanesulfonamide hydrochloride
• Synonyms: N-[(2S,3R,3'R,3aS,4'aR,6S,6'aR,6'bS,7aR,12'aS,12'bS)-2',3',3a,4,4',4'a,5,5',6,6',6'a,6'b,7,7',7a,8',10',12',12'a,12'b-Eicosahydro-3,6,11',12'b-tetramethylspiro[furo[3,2-b]pyridine-2(3H),9'(1'H)-naphth[2,1-a]azulen]-3'-yl]methanesulfonamide Hydrochloride

DATABASE IDS

• CAS Number: 1169829-40-6

DETAILS

Description (English)

A hedgehog inhibitor used in combination with other chemotherapeutics (e.g., docetaxel, mitoxantrone, estramustine, doxorubicin, etoposide, vinblastine, carboplatin, vinorelbine) for treating pancreatic cancer.

REFERENCES

• Shafaee, et al.: Cancer Chemother. Pharmacol., 58, 765 (2006)