5-Iodotubercidin

• Catalog No.: I725000
• CAS Number: 24386-93-4
• M. F.: C11H13IN4O4
• M. W.: 392.14979
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (2R,3S,5R)-2-{4-amino-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl}-5-(hydroxymethyl)oxolane-3,4-diol
• IUPAC Traditional name: (2R,3S,5R)-2-{4-amino-5-iodopyrrolo[2,3-d]pyrimidin-7-yl}-5-(hydroxymethyl)oxolane-3,4-diol
• Synonyms: 7-Iodotubercidin; 4-Amino-5-iodo-7-(β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine; NSC 113939 5-Iodo-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

DATABASE IDS

• CAS Number: 24386-93-4

PROPERTIES

• Apperance: White to Off-White Solid
• Melting Point: 216-217°C dec.
• Solubility: DMSO
• Storage Condition: -20°C Freezer
• Storage Warning: Store tightly sealed at 4°C; Light Sensitive

DETAILS

Description (English)

An analogue of the antibiotic tubercidin, a pyrrolo[2,3-d]pyrimidine nucleoside antibiotic. A potent inhibitor of adenosine kinase from rat or guinea pig brain. Inhibits uptake of 3H-adenosine into brain slices.

REFERENCES

• Long, M., et al.: Biochem. Pharmacol., 71, 1671 (2006)
• Lehar, J., et al.: Mol. Sys. Biol., (2006)
• Bonilla-Santiago, R., et al.: Mol. Biochem. Parasitol., 162, 149 (2006)
• Caballero, J., et al.: Bioorg. Med. Chem., 16, 5103 (2006)