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(αR)-α-(Iodomethyl)-3,4-dimethoxybenzenemethanol_Molecular_structure_CAS_833353-17-6)
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(αR)-α-(Iodomethyl)-3,4-dimethoxybenzenemethanol

Catalog No. I708380 Name Toronto Research Chemicals
CAS Number 833353-17-6 Website http://www.trc-canada.com
M. F. C10H13IO3 Telephone +1 (416) 665-9696
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Storage Chembase ID: 171677

SYNONYMS

IUPAC name
(1R)-1-(3,4-dimethoxyphenyl)-2-iodoethan-1-ol
IUPAC Traditional name
(1R)-1-(3,4-dimethoxyphenyl)-2-iodoethanol

DATABASE IDS

CAS Number 833353-17-6

PROPERTIES

Certificate of Analysis Download
Apperance White Solid
Solubility Dichloromethane
Solubility Ethyl Acetate
MSDS Link Download

DETAILS

Description (English)
(αR)-α-(Iodomethyl)-3,4-dimethoxy-benzenemethanol is used in the preparation of (R)-Isoprenaline, (R)-Norfluoxetine and (R)-Fluoxetine using stereoselective dihydroxylation method as key synthetic step.

REFERENCES

  • Zerbe, R., et al.: J. Pharmacol. Exp. Ther., 232, 139 (1985)
  • Bracher, F., et al.: Bioorg. Med. Chem., 4, 877 (1985)
  • Robertson, D., et al.: J. Med. Chem., 31, 1412 (1985)