myo-Inositol-d6 Trispyrophosphate Hexasodium Salt

• Catalog No.: I666022
• M. F.: C6H6Na6O21P6
• M. W.: 737.880426
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: hexasodium (1R,2R,8R,9R,15R,16S)-hexaoxo(^2H₆)-3,5,7,10,12,14,17,19,21-nonaoxa-4λ^5,6λ^5,11λ^5,13λ^5,18λ^5,20λ^5-hexaphosphatetracyclo[14.5.0.0^2,^8.0^9,^1^5]henicosane-4,6,11,13,18,20-hexakis(olate)
• IUPAC Traditional name: hexasodium (1R,2R,8R,9R,15R,16S)-hexaoxo(^2H₆)-3,5,7,10,12,14,17,19,21-nonaoxa-4λ^5,6λ^5,11λ^5,13λ^5,18λ^5,20λ^5-hexaphosphatetracyclo[14.5.0.0^2,^8.0^9,^1^5]henicosane-4,6,11,13,18,20-hexakis(olate)
• Synonyms: myo-Inositol-d6 Cyclic 1,2:3,4:5,6-Tris(P,P'-dihydrogen diphosphate) Hexasodium Salt; ITTP-d6 Hexasodium Salt; myo-Inositol-d6 Cyclic 1,2:3,4:5,6-Tris(dihydrogen pyrophosphate)) Hexasodium Salt

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: >274°C (dec.)
• Solubility: Water
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

Labelled myo-Inositol Trispyrophosphate hexasodium (I666020). A novel membrane-permeant allosteric effector of hemoglobin (Hb), enhances the regulated oxygen release capacity of red blood cells, thus counteracting the effects of hypoxia in diseases such a

REFERENCES

• Duarte,C.D. et al.: Chembiochem., 11, 2543 (2010)
• Biolo, A. et al.: Proc. Nat. Acad. Sci. U.S.A., 106, 1926 (2010)