myo-Inositol Trispyrophosphate Hexasodium Salt

• Catalog No.: I666020
• CAS Number: 23103-35-7
• M. F.: C6H6Na6O21P6
• M. W.: 737.880426
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: hexasodium (1R,2R,8R,9R,15R,16S)-4,6,11,13,18,20-hexaoxo-3,5,7,10,12,14,17,19,21-nonaoxa-4λ^5,6λ^5,11λ^5,13λ^5,18λ^5,20λ^5-hexaphosphatetracyclo[14.5.0.0^2,^8.0^9,^1^5]henicosane-4,6,11,13,18,20-hexakis(olate)
• IUPAC Traditional name: hexasodium (1R,2R,8R,9R,15R,16S)-4,6,11,13,18,20-hexaoxo-3,5,7,10,12,14,17,19,21-nonaoxa-4λ^5,6λ^5,11λ^5,13λ^5,18λ^5,20λ^5-hexaphosphatetracyclo[14.5.0.0^2,^8.0^9,^1^5]henicosane-4,6,11,13,18,20-hexakis(olate)
• Synonyms: myo-Inositol Cyclic 1,2:3,4:5,6-Tris(dihydrogen pyrophosphate)) Hexasodium Salt; ITTP Hexasodium Salt; myo-Inositol Cyclic 1,2:3,4:5,6-Tris(P,P'-dihydrogen diphosphate) Hexasodium Salt

DATABASE IDS

• CAS Number: 23103-35-7

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 281-286°C (dec.)
• Solubility: Water
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

A novel membrane-permeant allosteric effector of hemoglobin (Hb), enhances the regulated oxygen release capacity of red blood cells, thus counteracting the effects of hypoxia in diseases such as cancer and cardiovascular ailments.

REFERENCES

• Duarte,C.D. et al.: Chembiochem., 11, 2543 (2010)
• Biolo, A. et al.: Proc. Nat. Acad. Sci. U.S.A., 106, 1926 (2010)