Idazoxan-d4 Hydrochloride

• Catalog No.: I506802
• M. F.: C11H13ClN2O2
• M. W.: 240.68612

SYNONYMS

• IUPAC name: 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro(4,4,5,5-^2H₄)-1H-imidazole hydrochloride
• IUPAC Traditional name: 2-(2,3-dihydro-1,4-benzodioxin-2-yl)(4,4,5,5-^2H₄)-1H-imidazole hydrochloride
• Synonyms: RX 781094-d4; (+/-)-Idazoxan-d4 Monohydrochloride; RX 781094A-d4; 2-(2,3-Dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole-d4 Hydrochloride

DETAILS

Description (English)

Labelled Idazoxan (I506800). An α-adrenoceptor antagonist; in rat brain Idazoxan is a pure antagonist and it has a selectivity for α2- over α1-receptors markedly superior to Piperoxane, Yohimbine, or Rauwolscine. Antiparkinsonian.

REFERENCES

• Fliri, A., et al.: Med. Chem., 48, 6918 (2005)
• Yildirim, M., et al.: Nat. Biotechnol., 25, 1119 (2005)