O-(α-L-Idopyranosyluronic Acid 2-Sulfate-(1-4)-N-acetylglucosamine Disodium Salt

• Catalog No.: I192600
• M. F.: C14H21NNa2O15S
• M. W.: 521.35878

SYNONYMS

• IUPAC name: disodium (2R,3S,4S,5R,6R)-6-{[(2R,3S,4R,5R,6S)-5-acetamido-4,6-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy}-3,4-dihydroxy-5-(sulfonatooxy)oxane-2-carboxylate
• IUPAC Traditional name: disodium (2R,3S,4S,5R,6R)-6-{[(2R,3S,4R,5R,6S)-5-acetamido-4,6-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy}-3,4-dihydroxy-5-(sulfonatooxy)oxane-2-carboxylate
• Synonyms: 2-(Acetylamino)-2-deoxy-4-O-(2-O-sulfo-α-L-idopyranuronosyl)-α-D-Glucopyranose Disodium Salt

DETAILS

Description (English)

A Heparin sulfate analogue as a Novel β-Secretase ιnhibitor as potential Alzheimer's disease therapeutics.

REFERENCES

• Scholefield, Z., et al.: J. Cell Biol., 163, 97 (2003)
• Patey, S., et al.: J. Med. Chem., 49, 6129 (2003)
• Rudd, T., et al.: Glycobiology, 17, 983 (2003)