Idarubicin Hydrochloride

• Catalog No.: I167000
• CAS Number: 57852-57-0
• M. F.: C26H28ClNO9
• M. W.: 533.95482
• Storage: Amber Vial, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (7S,9S)-9-acetyl-7-{[(2R,4R,5S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,9,11-trihydroxy-5,7,8,9,10,12-hexahydrotetracene-5,12-dione hydrochloride
• IUPAC Traditional name: (7S,9S)-9-acetyl-7-{[(2R,4R,5S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,9,11-trihydroxy-8,10-dihydro-7H-tetracene-5,12-dione hydrochloride
• Synonyms: NSC 256439; Zavedos; Idamycin; 4-DMD HCl; (7S,9S)-9-Acetyl-7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-5,12-naphthacenedione Hydrochloride; 4-Demethoxydaunorubicin Hydrochloride

DATABASE IDS

• CAS Number: 57852-57-0

PROPERTIES

• Apperance: Orange Solid
• Melting Point: 193-195°C
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: Amber Vial, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

Orally active anthracycline; analog of Daunorubicin. Antineoplastic.

REFERENCES

• Arcamone, F., et al.: Caner Treat. Rep., 60, 829 (1976)
• Zini, G., et al.: Cancer Chemother. Pharmacol., 16, 107 (1976)
• Gillies, H.C., et al.: Br.J. Clin. Pharmacol., 23, 303 (1976)
• Villani, F., et al.: Eur. J. Cancer Clin. Oncol., 25, 13 (1976)