Home > Compound List > Product Information
(R)-(-)-Ibuprofen (S)-(+)-Lysinate_Molecular_structure_CAS_157369-85-2)
Click picture or here to close

(R)-(-)-Ibuprofen (S)-(+)-Lysinate

Catalog No. I140020 Name Toronto Research Chemicals
CAS Number 157369-85-2 Website http://www.trc-canada.com
M. F. C19H32N2O4 Telephone +1 (416) 665-9696
M. W. 352.46838 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Refrigerator Chembase ID: 171495

SYNONYMS

IUPAC name
(2R)-2-[4-(2-methylpropyl)phenyl]propanoic acid; (2S)-2,6-diaminohexanoic acid
IUPAC Traditional name
(-)-ibuprofen; L-lysine
Synonyms
(αR)-α-Methyl-4-(2-methylpropyl)benzeneacetic Acid L-Lysine

DATABASE IDS

CAS Number 157369-85-2

PROPERTIES

Certificate of Analysis Download
Apperance White Solid
Melting Point 185-187°C
Solubility Methanol
Solubility Water
MSDS Link Download
Storage Condition Refrigerator

DETAILS

Description (English)
A nonsteroidal anti-inflammatory drug (NSAID). Optically active, selective cyclooxygenase inhibitor (IC50=14.9uM). Inhibits PGH synthase-1 and PGH synthase-2 with comparable potency.

REFERENCES

  • Busson, M., et al.: J. Int. Med Res., 14, 53 (1986)
  • Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1986)
  • Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1986)