Hymenialdisine Analogue #1

• Catalog No.: H998025
• CAS Number: 693222-51-4
• M. F.: C15H13N5O2
• M. W.: 295.29602
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: 2-amino-4-{1-oxo-1H,2H,3H,4H,5H,10H-azepino[3,4-b]indol-5-ylidene}-4,5-dihydro-1H-imidazol-5-one
• IUPAC Traditional name: 2-amino-5-{1-oxo-2H,3H,4H,10H-azepino[3,4-b]indol-5-ylidene}-3H-imidazol-4-one
• Synonyms: 5-(2-Amino-5-oxo-1,5-dihydroimidazol-4-ylidene)-3,4,5,10-tetrahydro-2H-azepino[3,4-b]indol-1-one

DATABASE IDS

• CAS Number: 693222-51-4

PROPERTIES

• Apperance: Light Yellow Solid
• Solubility: Butanol
• Solubility: DMSO
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

The indole derivative of Hymenialdisine, a potent inhibitor of a variety of kinases including MEK-1, GSK-3Β, and CKI. It also exhibits inhibition of the G2 cell cycle checkpoint at the micromolar concentrations. This compound exhibits very potent inhibi

REFERENCES

• Sharma, V., and Tepe, J.J.: Bioorg. & Medicinal Chem. Letters, 14, 4319 (2004)
• Sharma, V., et al.: J. Med. Chem., 47, 3700 (2004)