4-Hydroxy Valsartan (Mixture of Diastereomers)

• Catalog No.: H995000
• CAS Number: 188259-69-0
• M. F.: C24H29N5O4
• M. W.: 451.51816
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (2S)-2-[4-hydroxy-N-({4-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)pentanamido]-3-methylbutanoic acid
• IUPAC Traditional name: (2S)-2-[4-hydroxy-N-({4-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)pentanamido]-3-methylbutanoic acid
• Synonyms: CGP 71580; (S)-2-{(4(R,S)-Hydroxypentanoyl)-[2’-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]amino}-3-methylbutyric Acid; N-(4-Hydroxy-1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine

DATABASE IDS

• CAS Number: 188259-69-0

PROPERTIES

• Apperance: White to Off-White Solid
• Melting Point: 94-98°C
• Solubility: Ethanol
• Solubility: Methanol
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

A nonpeptide angiotensin II AT1-receptor antagonist.

REFERENCES

• Criscione, L., et al.: Brit. J. Pharmacol., 110, 761 (1993)
• Muller, P., et al.: Eur. J. Clin. Pharmacol., 47, 231 (1994)