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Hydroxy Urea-15N

Catalog No. H991010 Name Toronto Research Chemicals
CAS Number 214331-53-0 Website http://www.trc-canada.com
M. F. CH4N2O2 Telephone +1 (416) 665-9696
M. W. 77.0480689 Fax +1 (416) 665-4439
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SYNONYMS

IUPAC name
hydroxy(15N1)urea
IUPAC Traditional name
hydroxy(15N1)urea
Synonyms
Carbamoyl Oxime-15N
Cytodrox-15N
Hydurea-15N
Hydroxycarbamide-15N
HU-15N
N-Carbamoylhydroxylamine-15N
Biosupressin-15N
Hydrea-15N
Hydroxycarbamine-15N
N-(Aminocarbonyl)hydroxylamine-15N
Hydura-15N
Litaler-15N
NCI C04831-15N
Oxyurea-15N
SK 22591-15N
N-Hydroxyurea-15N
Carbamohydroxamic Acid-15N
Droxia-15N
Hidrix-15N
Hydreia-15N
Litalir-15N
NSC 32065-15N
SQ 1089-15N

DATABASE IDS

CAS Number 214331-53-0

PROPERTIES

Certificate of Analysis Download
Apperance Off-White Crystalline Solid
Melting Point 133-136°C
Solubility Hot Alcohol
Solubility Water
MSDS Link Download

DETAILS

Description (English)
Labelled Hydroxyurea. An anti-neoplastic - inhibits ribonucleoside reductase and DNA replication. A potential therapy for sickle cell anemia which involves the nitrosylation of sickle cell hemoglobin. Horseradish peroxidase catalyzes nitric oxide formatio

REFERENCES

  • Ratcliffe, W., et al.: Lancet, 339, 164 (1992)
  • Roodman, G., et al.: Cancer, 80, 1557 (1992)
  • Horwitz, M., et al.: J. Clin. Endocrinol. Metab., 2003, 88, 1603 (1992)