Hydroxy Urea-13C,15N2

• Catalog No.: H991002
• M. F.: CH4N2O2
• M. W.: 79.03413263
• Storage: -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: hydroxy(^1^3C,^1^5N₂)urea
• IUPAC Traditional name: hydroxy(^1^3C,^1^5N₂)urea
• Synonyms: SQ 1089-13C,15N2; Hydroxycarbamine-13C,15N2; Hydroxycarbamide-13C,15N2; Hydreia-13C,15N2; Droxia-13C,15N2; N-Hydroxyurea-13C,15N2; Carbamoyl Oxime-13C,15N2; Hydrea-13C,15N2; N-(Aminocarbonyl)hydroxylamine-13C,15N2; Hydura-13C,15N2; Litaler-13C,15N2; N-Carbamoylhydroxylamine-13C,15N2; NSC 32065-13C,15N2; Oxyurea-13C,15N2; SK 22591-13C,15N2; Biosupressin-13C,15N2; Carbamohydroxamic Acid-13C,15N2; Cytodrox-13C,15N2; Hydroxylurea-13C,15N2

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 126-131°C (dec.)
• Solubility: DMSO
• Storage Condition: -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

Labelled Hydroxyurea. An anti-neoplastic - inhibits ribonucleoside reductase and DNA replication. A potential therapy for sickle cell anemia which involves the nitrosylation of sickle cell hemoglobin. Horseradish peroxidase catalyzes nitric oxide formatio

REFERENCES

• Ratcliffe, W., et al.: Lancet, 339, 164 (1992)
• Roodman, G., et al.: Cancer, 80, 1557 (1992)
• Horwitz, M., et al.: J. Clin. Endocrinol. Metab., 2003, 88, 1603 (1992)