3α-Hydroxy Tibolone 17-O-Sulfate

• Catalog No.: H964255
• CAS Number: 144466-05-7
• M. F.: C21H30O5S
• M. W.: 394.5249

SYNONYMS

• IUPAC name: [(1S,5R,9R,10R,11S,14R,15S)-14-ethynyl-5-hydroxy-9,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-2(7)-en-14-yl]oxidanesulfonic acid
• IUPAC Traditional name: [(1S,5R,9R,10R,11S,14R,15S)-14-ethynyl-5-hydroxy-9,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-2(7)-en-14-yl]oxidanesulfonic acid
• Synonyms: (3α,7α,17α)-7-Methyl-19-norpregn-5(10)-en-20-yne-3,17-diol 17-(Hydrogen Sulfate)

DATABASE IDS

• CAS Number: 144466-05-7

DETAILS

Description (English)

3α-Hydroxy Tibolone 17-O-Sulfate is the 17-sulfate conjugate of 3α-Hydroxy Tibolone and a metabolite of Tibolone (T437500), a synthetic steroid used in the treatment of menopausal syndrome.

REFERENCES

• Verheul, H.A.M. et al.: Drug Metab. Dispos., 35, 1112 (2007)
• Vos, R.M.E. et al.: Drug Metab. Dispos., 30, 106 (2007)
• Verhoeven, C.H.J. et al.: Eur. J. Drug Metab. Pharmacokin., 27, 1 (2007)