Home > Compound List > Product Information
Hydroxy Terbinafine _Molecular_structure_CAS_162227-13-6)
Click picture or here to close

Hydroxy Terbinafine

Catalog No. H956160 Name Toronto Research Chemicals
CAS Number 162227-13-6 Website http://www.trc-canada.com
M. F. C21H25NO Telephone +1 (416) 665-9696
M. W. 307.4293 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Chembase ID: 171343

SYNONYMS

IUPAC name
(5E)-2,2-dimethyl-7-[methyl(naphthalen-1-ylmethyl)amino]hept-5-en-3-yn-1-ol
IUPAC Traditional name
(5E)-2,2-dimethyl-7-[methyl(naphthalen-1-ylmethyl)amino]hept-5-en-3-yn-1-ol
Synonyms
(5E)-2,2-Dimethyl-7-[methyl(1-naphthalenylmethyl)amino]-5-hepten-3-yn-1-ol

DATABASE IDS

CAS Number 162227-13-6

PROPERTIES

Certificate of Analysis Download
Apperance Pale Yellow Oil
Solubility Chloroform
Solubility Dichloromethane
Solubility Methanol
MSDS Link Download

DETAILS

Description (English)
A metabolite of Terbinafine, an orally active, antimycotic allylamine related to naftifine. A specfic inhibitor of squalene epoxidase, a key enzyme in fungal ergosterol biosynthesis.

REFERENCES

  • Gazinger, U., et al.: Proc. 13th Int. Congr. Chemother., 6, 116/52 (1983)
  • Shadomy, S., et al.: Sabouraudia, 23, 125 (1983)
  • Evans, E.G.V., et al.: Brit. Med. J., 318, 1031 (1999)