(E)-4-Hydroxy Tamoxifen O-β-D-Glucuronide

• Catalog No.: H954760
• CAS Number: 152764-51-7
• M. F.: C32H37NO8
• M. W.: 563.63808
• Storage: Amber Vial, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (2S,3S,4S,5R,6S)-6-{4-[(1E)-1-{4-[2-(dimethylamino)ethoxy]phenyl}-2-phenylbut-1-en-1-yl]phenoxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
• IUPAC Traditional name: (2S,3S,4S,5R,6S)-6-{4-[(1E)-1-{4-[2-(dimethylamino)ethoxy]phenyl}-2-phenylbut-1-en-1-yl]phenoxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
• Synonyms: O-β-D-Glucuronide of (Ζ)-4-Hydroxy Tamoxifen; 4-[(1E)-1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenyl β-D-Glucopyranosiduronic Acid

DATABASE IDS

• CAS Number: 152764-51-7

PROPERTIES

• Apperance: White Solid
• Melting Point: 173-176°C
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: Amber Vial, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

A glucuronide of (Z)-4-Hydroxy Tamoxifen (or trans-4-hydroxytamoxifen), an active metabolite of Tamoxifen (T006000).

REFERENCES

• Beaulieu, M., et al.: J. Biol. Chem., 271, 22855 (1996)
• Green, M., et al.: Drug Metab. Dispos., 26, 860 (1996)
• Nishiyama, T., et al.: Biochem. Pharmacol., 63, 1817 (1996)