(E)-3-Hydroxy Tamoxifen

• Catalog No.: H954720
• CAS Number: 82413-20-5
• M. F.: C26H29NO2
• M. W.: 387.51396
• Storage: Amber Vial, -20°C Freezer

SYNONYMS

• IUPAC name: 3-[(1E)-1-{4-[2-(dimethylamino)ethoxy]phenyl}-2-phenylbut-1-en-1-yl]phenol
• IUPAC Traditional name: droloxifene
• Synonyms: 3-[(1E)-1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-phenol; K060E; Droloxifene; E-Droloxifene; K-060; K 21.060E

DATABASE IDS

• CAS Number: 82413-20-5

PROPERTIES

• Apperance: Off-White to Pale-Beige Solid
• Melting Point: 127-129°C
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: Amber Vial, -20°C Freezer

DETAILS

Description (English)

A Tamoxifen (T006000) derivative with antitumor effect on estrogen-dependent breast cancer cells.

REFERENCES

• Ruenitz, P.C., et al.: J. Med. Chem., 25, 1056 (1982)
• Shiina, I., et al.: Bioorg. Med. Chem., 15, 7599 (1982)
• Jones, D., et al.: Drug Metab. Disposition, 35, 1466 (1982)
• Hartman, I., et al.: Pharm. Res., 26, 2247 (2009)