5-Hydroxy Rosiglitazone β-D-Glucuronide (mixture of diastereomers)

• Catalog No.: H953445
• CAS Number: 288853-59-8
• M. F.: C24H27N3O10S
• M. W.: 549.55028
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (2S,3S,4S,5R,6S)-6-({6-[(2-{4-[(2,4-dioxo-1,3-thiazolidin-5-yl)methyl]phenoxy}ethyl)(methyl)amino]pyridin-3-yl}oxy)-3,4,5-trihydroxyoxane-2-carboxylic acid
• IUPAC Traditional name: (2S,3S,4S,5R,6S)-6-({6-[(2-{4-[(2,4-dioxo-1,3-thiazolidin-5-yl)methyl]phenoxy}ethyl)(methyl)amino]pyridin-3-yl}oxy)-3,4,5-trihydroxyoxane-2-carboxylic acid
• Synonyms: 6-[6-({2-[4-(2,4-Dioxo-thiazolidin-5-ylmethyl)-phenoxy]ethyl}-methyl-amino)-pyridin-3-yloxy]-3,4,5-trihydroxy-tetrahydro-pyran-2-carboxylic Acid

DATABASE IDS

• CAS Number: 288853-59-8

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 155-158°C
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

A metabolite of Rosiglitazone.The ratio of the diastereomers will be quite variable due to the acidic proton at one chiral centre.

REFERENCES

• Balton, G.C., et al.: Xenobiotica, 26, 6, 627 (1996)