Hydroxy Ritonavir

• Catalog No.: H953390
• CAS Number: 176655-56-4
• M. F.: C37H48N6O6S2
• M. W.: 736.94362

SYNONYMS

• IUPAC name: 1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[(2S)-2-[({[2-(2-hydroxypropan-2-yl)-1,3-thiazol-4-yl]methyl}(methyl)carbamoyl)amino]-3-methylbutanamido]-1,6-diphenylhexan-2-yl]carbamate
• IUPAC Traditional name: 1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[(2S)-2-[({[2-(2-hydroxypropan-2-yl)-1,3-thiazol-4-yl]methyl}(methyl)carbamoyl)amino]-3-methylbutanamido]-1,6-diphenylhexan-2-yl]carbamate
• Synonyms: [5S-(5R*,8R*,10R*,11R*)]-10-Hydroxy-1-[2-(1-hydroxy-1-methylethyl)-4-thiazolyl]-2-methyl-5-(1-methylethyl)-3,6-dioxo-8,11-bis(phenylmethyl)-2,4,7,12-tetraazatridecan-13-oic Acid 5-Thiazolylmethyl Ester

DATABASE IDS

• CAS Number: 176655-56-4

DETAILS

Description (English)

A metabolite of Ritonavir (R535000), HIV-1 protease inhibitor.

REFERENCES

• Eagling, V., et al.: Br. J. Clin. Pharmacol., 48, 543 (1999)
• Eagling, V., et al.: Xenobiotica, 32, 1 (1999)
• Meaden, E., et al.: J. Antimicrob. Chemother., 50, 583 (1999)
• Treijtel, N., et al.: Drug Metab. Dispos., 33, 1325 (1999)