7-Hydroxy Quetiapine

• Catalog No.: H953225
• CAS Number: 139079-39-3
• M. F.: C21H25N3O3S
• M. W.: 399.5065
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: 10-{4-[2-(2-hydroxyethoxy)ethyl]piperazin-1-yl}-2-thia-9-azatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3(8),4,6,9,12,14-heptaen-5-ol
• IUPAC Traditional name: 10-{4-[2-(2-hydroxyethoxy)ethyl]piperazin-1-yl}-2-thia-9-azatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3(8),4,6,9,12,14-heptaen-5-ol
• Synonyms: 11-[4-[2-(2-Hydroxyethoxy)ethyl]-1-piperazinyl]dibenzo[b,f][1,4]thiazepin-7-ol; ICI214227

DATABASE IDS

• CAS Number: 139079-39-3

PROPERTIES

• Apperance: White Solid
• Melting Point: 56-60°C
• Solubility: Chloroform
• Solubility: Dichloromethane
• Solubility: Ethyl Acetate
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A metabolite of Quetiapine, a Benzothiazepine with mixed serotonin and dopamine receptor antagonistic properties used as an antipsychotic.

REFERENCES

• Newton, D., et al.: Drug Metab. Dispos., 23, 154 (1995)
• Tanaka, E., et al.: J. Clin. Pharm. Ther., 24, 7 (1999)