trans-Hydroxy Praziquantel-d5

• Catalog No.: H952407
• M. F.: C19H24N2O3
• M. W.: 328.40546

SYNONYMS

• IUPAC name: 2-[4-hydroxy(3,3,4,5,5-^2H₅)cyclohexanecarbonyl]-1H,2H,3H,4H,6H,7H,11bH-piperazino[2,1-a]isoquinolin-4-one
• IUPAC Traditional name: 2-[4-hydroxy(3,3,4,5,5-^2H₅)cyclohexanecarbonyl]-1H,3H,6H,7H,11bH-piperazino[2,1-a]isoquinolin-4-one
• Synonyms: trans-1,2,3,6,7,11b-Hexahydro-2-[(4-hydroxycyclohexyl)carbonyl]- 4H-pyrazino[2,1-a]isoquinolin-4-one-d5; 1,2,3,6,7,11b-Hexahydro-2-[(cis-4-hydroxycyclohexyl)carbonyl]-4H-pyrazino[2,1-a]isoquinolin-4-one-d5

DETAILS

Description (English)

Labelled trans-Hydroxy Praziquantel (H952405). The main cis-monohydroxylated metabolite of Praziquantel (P702095).

REFERENCES

• Buehring, K., et al.: Eur. J. Drug Metab. Pharm., 3, 179 (1978)
• Moldeus, P., et al.: Methods Enzymol., 52, 60 (1978)
• Cioli, D., et al.: Pharmacol. Ther., 68, 35 (1978)