3β-Hydroxy Pravastatin Sodium Salt

• Catalog No.: H952315
• M. F.: C23H35NaO7
• M. W.: 446.50957

SYNONYMS

• IUPAC name: sodium (3R,5R)-7-[(1S,2R,3R,8S,8aR)-3-hydroxy-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,3,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate
• IUPAC Traditional name: sodium (3R,5R)-7-[(1S,2R,3R,8S,8aR)-3-hydroxy-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,3,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate
• Synonyms: [1S-[1α(βS*,δS*),2α,3α,8β(R*),8aα]]-1,2,3,7,8,8a-Hexahydro-β,δ,3-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-1-naphthaleneheptanoic Acid; 3β-iso-Pravastatin Sodium Salt

PROPERTIES

• Solubility: Methanol
• Solubility: Water

DETAILS

Description (English)

A metabolite of Pravastatin, a competitive inhibitor of HMG-CoA reductase. Bioactive metabolite of Mevastatin.

REFERENCES

• Serizawa, N., et al.: J. Antibiot., 36, 604 (1983)
• White, H.D, et al.: N. Engl. J. Med., 343, 317 (2000)