3α-Hydroxy Pravastatin Sodium Salt

• Catalog No.: H952310
• CAS Number: 81093-43-8
• M. F.: C23H35NaO7
• M. W.: 446.50957
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: sodium (3R,5R)-7-[(1S,2R,3S,8S,8aR)-3-hydroxy-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,3,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate
• IUPAC Traditional name: sodium (3R,5R)-7-[(1S,2R,3S,8S,8aR)-3-hydroxy-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,3,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate
• Synonyms: (βR,δR,1S,2R,3S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-β,δ,3-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic Acid Sodium Salt; 3α-iso-Pravastatin

DATABASE IDS

• CAS Number: 81093-43-8

PROPERTIES

• Solubility: Methanol
• Solubility: Water
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

A metabolite of Pravastatin, a competitive inhibitor of HMG-CoA reductase. Bioactive metabolite of mevastatin.

REFERENCES

• Serizawa, N., et al.: J. Antibiot., 36, 604 (1983)
• White, H.D, et al.: N. Engl. J. Med., 343, 317 (2000)