3α-Hydroxy Pravastatin Lactone

• Catalog No.: H952300
• CAS Number: 85798-96-5
• M. F.: C23H34O6
• M. W.: 406.51246
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (1S,6S,7R,8S,8aR)-6-hydroxy-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-7-methyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate
• IUPAC Traditional name: (1S,6S,7R,8S,8aR)-6-hydroxy-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-7-methyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate
• Synonyms: (2S)-2-Methylbutanoic Acid (1S,6S,7R,8S,8aR)-1,2,6,7,8,8a-Hexahydro-6-hydroxy-7-methyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester; 3α-iso-Pravastatin; SQ 31906 Lactone

DATABASE IDS

• CAS Number: 85798-96-5

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 38-40°C
• Solubility: Chloroform
• Solubility: Methanol
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

A metabolite of Pravastatin (P702000), a competitive inhibitor of HMG-CoA reductase.

REFERENCES

• Serizawa, N., et al.: J. Antibiot., 36, 604 (1983)
• White, H.D, et al.: N. Engl. J. Med., 343, 317 (2000)