6α-Hydroxy Paclitaxel-d5

• Catalog No.: H948892
• M. F.: C47H51NO15
• M. W.: 869.90554
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (1S,2S,3R,4S,7R,8S,9R,10S,12R,15S)-4,12-bis(acetyloxy)-1,8,9-trihydroxy-15-{[(2R,3S)-2-hydroxy-3-phenyl-3-[(^2H₅)phenylformamido]propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0^3,^1^0.0^4,^7]heptadec-13-en-2-yl benzoate
• IUPAC Traditional name: (1S,2S,3R,4S,7R,8S,9R,10S,12R,15S)-4,12-bis(acetyloxy)-1,8,9-trihydroxy-15-{[(2R,3S)-2-hydroxy-3-phenyl-3-[(^2H₅)phenylformamido]propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0^3,^1^0.0^4,^7]heptadec-13-en-2-yl benzoate
• Synonyms: 6α-Hydroxy Taxol-d5

PROPERTIES

• Apperance: White Solid
• Melting Point: 174-176°C
• Solubility: Chloroform
• Solubility: Dichloromethane
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

The major human labelled metabolite of Paclitaxel.

REFERENCES

• Monsarrat, B., et al.: Drug Metab. Dispos., 18, 895 (1990)
• Walle, T., et al.: Biochem. Pharm., 46, 1661 (1990)
• Harris, J., et al.: J. Med. Chem., 37, 706 (1990)