cis-4-Hydroxy-L-proline-d5(Mixture of Diastereomers)

• Catalog No.: H952377
• M. F.: C5H9NO3
• M. W.: 131.12986

SYNONYMS

• IUPAC name: (2S,4S)-4-hydroxy(3,3,4,5,5-^2H₅)pyrrolidine-2-carboxylic acid
• IUPAC Traditional name: (2S,4S)-4-hydroxy(3,3,4,5,5-^2H₅)pyrrolidine-2-carboxylic acid
• Synonyms: (2S,4S)-4-Hydroxyproline-d5; L-Allohydroxyproline-d5; (S)-Allo-hydroxyproline-d5; cis-4-Hydroxyproline-d5; (4S)-4-Hydroxy-L-proline-d5; (2S,4S)-4-Hydroxypyrrolidine-2-carboxylic Acid-d5; cis-Hydroxyproline-d5

DETAILS

Description (English)

Labelled Hydroxyprolines are valuable chiral building blocks for organic synthesis of pharmaceuticals. Several microorganisms producing proline trans-4- and cis-3-hydroxylase were discovered and these enzymes were applied to the industrial production of t

REFERENCES

• Lawrence, C., et al.: Biochem. J., 313, 185 (1996)
• Mori, H., et al.: J. Bacteriol., 179, 5677 (1996)
• Clifton, I., et al.: Eur. J. Biochem., 268, 6625 (1996)