10-Hydroxy Naltrexone Methyl Ether

• Catalog No.: H948535
• M. F.: C21H25NO5
• M. W.: 371.4269

SYNONYMS

• IUPAC name: (1S,5R,13R,17S)-4-(cyclopropylmethyl)-6,17-dihydroxy-10-methoxy-12-oxa-4-azapentacyclo[9.6.1.0^1,^1^3.0^5,^1^7.0^7,^1^8]octadeca-7(18),8,10-trien-14-one
• IUPAC Traditional name: (1S,5R,13R,17S)-4-(cyclopropylmethyl)-6,17-dihydroxy-10-methoxy-12-oxa-4-azapentacyclo[9.6.1.0^1,^1^3.0^5,^1^7.0^7,^1^8]octadeca-7(18),8,10-trien-14-one
• Synonyms: 10-Hydroxynaltrexone-3-methyl Ether; (5α)-17-(Cyclopropylmethyl)-4,5-epoxy-10,14-dihydroxy-3-methoxy-morphinan-6-one

PROPERTIES

• Apperance: Pale Brown Solid
• Solubility: Acetone
• Solubility: Dichloromethane
• Solubility: DMSO

DETAILS

Description (English)

Naltrexone derivative.

REFERENCES

• Archer S., et al.: J. Med. Chem., 28 974 (1985)