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8-Hydroxy-2-methyl-4(3H)-quinazolinone_Molecular_structure_CAS_90417-38-2)
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8-Hydroxy-2-methyl-4(3H)-quinazolinone

Catalog No. H948330 Name Toronto Research Chemicals
CAS Number 90417-38-2 Website http://www.trc-canada.com
M. F. C9H8N2O2 Telephone +1 (416) 665-9696
M. W. 176.17202 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage -20°C Freezer Chembase ID: 2415

SYNONYMS

IUPAC name
8-hydroxy-2-methyl-3,4-dihydroquinazolin-4-one
IUPAC Traditional name
8-hydroxy-2-methyl-3H-quinazolin-4-one
Synonyms
NSC 696807

DATABASE IDS

CAS Number 90417-38-2

PROPERTIES

Certificate of Analysis Download
Apperance Off-White to Pale Yellow Solid
Melting Point >250°C (dec.)
Solubility Ethanol
Solubility Ethyl Acetate
Solubility Methanol
MSDS Link Download
Storage Condition -20°C Freezer

DETAILS

Description (English)
A potent inhibitor of poly (ADP-ribose) polymerase (PARP). Ki and IC50 values are 48 and 400 nM respectively.

REFERENCES

  • Griffin, R.J., et al.: J. Med. Chem., 41, 5247 (1998)
  • De Soto, J., et al.: Int. J. Biol. Sci., 2, 179 (1998)