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4-Hydroxymethyl Loratadine_Molecular_structure_CAS_609806-40-8)
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4-Hydroxymethyl Loratadine

Catalog No. H947750 Name Toronto Research Chemicals
CAS Number 609806-40-8 Website http://www.trc-canada.com
M. F. C23H25ClN2O3 Telephone +1 (416) 665-9696
M. W. 412.9092 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage -20°C Freezer Chembase ID: 170827

SYNONYMS

IUPAC name
ethyl 4-[13-chloro-7-(hydroxymethyl)-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene]piperidine-1-carboxylate
IUPAC Traditional name
ethyl 4-[13-chloro-7-(hydroxymethyl)-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene]piperidine-1-carboxylate
Synonyms
4-[8-Chloro-5,6-dihydro-4-(hydroxymethyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene]-1-piperidinecarboxylic Acid Ethyl Ester

DATABASE IDS

CAS Number 609806-40-8

PROPERTIES

Certificate of Analysis Download
Apperance Pale Yellow Solid
Melting Point 96-99°C
Solubility Chloroform
Solubility Ethyl Acetate
MSDS Link Download
Storage Condition -20°C Freezer

DETAILS

Description (English)
A usual impurity in Loratadine syrup formulations, a nonsedating-type histamine H1-receptor.

REFERENCES

  • Okamoto, T., et al.: Chem. Pharm. Bull ., 7, 130 (1959)
  • Eyjolfsson, R., et al.: Pharmazie, 58, 154 (1959)