4-Hydroxymethyl Loratadine

• Catalog No.: H947750
• CAS Number: 609806-40-8
• M. F.: C23H25ClN2O3
• M. W.: 412.9092
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: ethyl 4-[13-chloro-7-(hydroxymethyl)-4-azatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene]piperidine-1-carboxylate
• IUPAC Traditional name: ethyl 4-[13-chloro-7-(hydroxymethyl)-4-azatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene]piperidine-1-carboxylate
• Synonyms: 4-[8-Chloro-5,6-dihydro-4-(hydroxymethyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene]-1-piperidinecarboxylic Acid Ethyl Ester

DATABASE IDS

• CAS Number: 609806-40-8

PROPERTIES

• Apperance: Pale Yellow Solid
• Melting Point: 96-99°C
• Solubility: Chloroform
• Solubility: Ethyl Acetate
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A usual impurity in Loratadine syrup formulations, a nonsedating-type histamine H1-receptor.

REFERENCES

• Okamoto, T., et al.: Chem. Pharm. Bull ., 7, 130 (1959)
• Eyjolfsson, R., et al.: Pharmazie, 58, 154 (1959)