N-Hydroxy Melagatran

• Catalog No.: H944585
• CAS Number: 192939-72-3
• M. F.: C22H31N5O5
• M. W.: 445.51204
• Storage: -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: 2-{[(1R)-1-cyclohexyl-2-[(2S)-2-({[4-(N-hydroxycarbamimidoyl)phenyl]methyl}carbamoyl)azetidin-1-yl]-2-oxoethyl]amino}acetic acid
• IUPAC Traditional name: {[(1R)-1-cyclohexyl-2-[(2S)-2-({[4-(N-hydroxycarbamimidoyl)phenyl]methyl}carbamoyl)azetidin-1-yl]-2-oxoethyl]amino}acetic acid
• Synonyms: N-[(1R)-1-Cyclohexyl-2-[(2S)-2-[[[[4-[(hydroxyamino)iminomethyl]phenyl]methyl]amino]carbonyl]-1-azetidinyl]-2-oxoethyl]glycine; Melagatran Hydroxyamidine

DATABASE IDS

• CAS Number: 192939-72-3

PROPERTIES

• Apperance: White Solid
• Melting Point: 210-212°C
• Solubility: DMSO
• Storage Condition: -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

An N-Hydroxyguanidine prodrug and intermediate in the preparation of Melagatran

REFERENCES

• Johansson, L., et al.: Clini.Pharmacokin., 42, 475 (2003)
• Gruenewald, S., et al.: J. Med. Chem., 51, 8173 (2003)
• Sjoegren, E., et al.: Drug Metab. Disposition, 37, 47 (2003)