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rac 3-Hydroxy Kynurenine

Catalog No. H943695 Name Toronto Research Chemicals
CAS Number 484-78-6 Website http://www.trc-canada.com
M. F. C10H12N2O4 Telephone +1 (416) 665-9696
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SYNONYMS

IUPAC name
2-amino-4-(2-amino-3-hydroxyphenyl)-4-oxobutanoic acid
IUPAC Traditional name
hydroxykynurenine
Synonyms
3-Hydroxykynurenine
NSC 96400
3-(3-Hydroxyanthraniloyl)alanine
α,2-Diamino-3-hydroxy-γ-oxobenzenebutanoic acid
3-Hydroxy-DL-kynurenine
DL-3-Hydroxykynurenine
Hydroxykynurenine

DATABASE IDS

CAS Number 484-78-6

PROPERTIES

Certificate of Analysis Download
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DETAILS

Description (English)
3-Hydroxykynurenine is a metabolite of tryptophan. 3-Hydroxykynurenine filters UV light in the human lens. Studies suggest that Hydroxykynurenine is an endogenous oxidative stress generator and a potential endogenous neurotoxin.

REFERENCES

  • Malina, H.Z. et al.: Graefes. Arch. Clin. Exp. Ophthalmol., 233, 38 (1995)
  • Okuda, S. et al.: J. Neurochem., 70, 299 (1995)