2-Hydroxy Irinotecan

• Catalog No.: H943540
• M. F.: C33H38N4O7
• M. W.: 602.67742

SYNONYMS

• IUPAC name: (19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0^2,^1^1.0^4,^9.0^1^5,^2^0]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-7-yl 2-hydroxy-4-(piperidin-1-yl)piperidine-1-carboxylate
• IUPAC Traditional name: (19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0^2,^1^1.0^4,^9.0^1^5,^2^0]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-7-yl 2-hydroxy-4-(piperidin-1-yl)piperidine-1-carboxylate
• Synonyms: Irinotecan 2-Hydroxy Impurity; (4S)-4,11-Diethyl-4-hydroxy-9-[(2-hydroxy-4-piperidinopiperidino)carbonyloxy]-1H-pyrano[3’,4’:6,7]indolizino[1,2-b]-quinoline-3,14(4H,12H)-dione

DETAILS

Description (English)

A hydroxy impurity of Irinotecan (I767500).

REFERENCES

• Kunimoto, T., et al.: Cancer Res., 47, 5944 (1987)
• Shimada, Y., et al.: J. Clin. Oncol., 11, 909 (1993)