8-Hydroxy Guanosine 5'-Triphosphate Triethylammonium Salt

• Catalog No.: H942780
• M. F.: C10H16N5O15P3
• M. W.: 539.179823

SYNONYMS

• IUPAC name: ({[({[(2R,3S,4R,5R)-5-(2-amino-8-hydroxy-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid
• IUPAC Traditional name: ({[(2R,3S,4R,5R)-5-(2-amino-8-hydroxy-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy(hydroxy)phosphoryl}oxy(hydroxy)phosphoryl)oxyphosphonic acid
• Synonyms: 2-Amino-9-β-D-ribofuranosylpurine-6,8(1H,9H)-dione 5'-(Tetrahydrogen Triphosphate) Triethylammonium Salt; 7,8-Dihydro-8-oxoguanosine 5'-(Tetrahydrogen Triphosphate) Triethylammonium Salt; 8-Ketoguanosine 5'-Triphosphate Bis(triethylammonium) Triethylammonium Salt; 8-OH-GTP Di-TEA Triethylammonium Salt

DETAILS

Description (English)

8-Hydroxy Guanosine 5’-Triphosphate is an oxidized ribonucleotide induced mutations in cDNA, suggesting disturbance of genetic information during transcription and/or reverse transcription. It is a potential antiviral drug that cause mutations in genomic

REFERENCES

• Taddei, F., et al.: Science, 278, 128 (1997)
• Kasai, H., et al.: Mutat. Res., 387, 147 (1997)
• Kamiya, H., et al.: Nucleic Acids Res., 231, 517 (1997)