8-Hydroxy Guanosine-13C,15N2

• Catalog No.: H942772
• M. F.: C10H13N5O6
• M. W.: 302.21959263
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: 2-amino-9-[(2R,3S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-hydroxy-6,9-dihydro(2-^1^3C,1-^1^5N)-1H-purin-6-one
• IUPAC Traditional name: 2-amino-9-[(2R,3S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-hydroxy(2-^1^3C,1-^1^5N)-1H-purin-6-one
• Synonyms: 8-OHG-13C,15N2; 8-Oxo-7,8-dihydroguanosine-13C,15N2; 8-Oxoguanosine-13C,15N2; 2-Amino-9-β-D-ribofuranosyl-purine-6,8(1H,9H)-dione-13C,15N2; NSC 90393-13C,15N2

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 235-240°C
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

Labelled 8-Hydroxy Guanosine (H942770). It is a representative metabolite derived by the oxidation of Guanosine (G) and is regarded as a marker of oxidative stress in the cells.

REFERENCES

• Lin, T.-S. et al.: J. Med. Chem., 28, 1194 (1985)
• Risom, L., et al.: Mutat. Res., 592, 119 (1985)
• Knaapen, A., et al.: Mutagenesis, 21, 225 (1985)