Hydroxy Itraconazole-d5

• Catalog No.: H943602
• M. F.: C35H38Cl2N8O5
• M. W.: 721.63282
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: 4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-1-[3-hydroxy(2,3,4,4,4-^2H₅)butan-2-yl]-4,5-dihydro-1H-1,2,4-triazol-5-one
• IUPAC Traditional name: 4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-2-[3-hydroxy(2,3,4,4,4-^2H₅)butan-2-yl]-1,2,4-triazol-3-one
• Synonyms: 4-[4-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(2-hydroxy-1-methylpropyl-d5)-3H-1,2,4-triazol-3-one; R 63373-d5

PROPERTIES

• Apperance: Off-White to Light Tan Solid
• Solubility: Chloroform
• Solubility: DMSO
• Solubility: Ethanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

An isotopically Labelled metabolite of Itraconazole, an orally active antimycotic structurally related to Ketoconazole.

REFERENCES

• Saag, M., et al.: Antimicrob. Agents Chemother., 32, 1 (1988)
• Haria, M., et al.: Drugs, 51, 585 (1988)
• Kousoulos, C., et al.: Anal. Bioanal. Chem., 384,199 (1988)