Hydroxy Itraconazole

• Catalog No.: H943600
• CAS Number: 112559-91-8
• M. F.: C35H38Cl2N8O5
• M. W.: 721.63282
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: 4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-1-(3-hydroxybutan-2-yl)-4,5-dihydro-1H-1,2,4-triazol-5-one
• IUPAC Traditional name: 4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-2-(3-hydroxybutan-2-yl)-1,2,4-triazol-3-one
• Synonyms: 4-[4-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(2-hydroxy-1-methylpropyl)-3H-1,2,4-triazol-3-one; R 63373

DATABASE IDS

• CAS Number: 112559-91-8

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 87-90°C
• Solubility: Chloroform
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A metabolite of Itraconazole, an orally active antimycotic structurally related to Ketoconazole.

REFERENCES

• Saag, M., et al.: Antimicrob. Agents Chemother., 32, 1 (1988)
• Haria, M., et al.: Drugs, 51, 585 (1988)
• Kousoulos, C., et al.: Anal. Bioanal. Chem., 384,199 (1988)