6α-Hydroxy Estrone

• Catalog No.: H941935
• CAS Number: 1476-78-4
• M. F.: C18H22O3
• M. W.: 286.36548

SYNONYMS

• IUPAC name: (1S,8S,10R,11S,15S)-5,8-dihydroxy-15-methyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-2,4,6-trien-14-one
• IUPAC Traditional name: (1S,8S,10R,11S,15S)-5,8-dihydroxy-15-methyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-2,4,6-trien-14-one
• Synonyms: 3,6α-Dihydroxyestra-1,3,5(10)-trien-17-one; (6α)-3,6-Dihydroxyestra-1,3,5(10)-trien-17-one; 6α-Hydroxyestrone

DATABASE IDS

• CAS Number: 1476-78-4

DETAILS

Description (English)

The oxidative 6α-metabolite of 17β-Estradiol (E887995) and Estrone (E889050) formed by 15 selectively expressed human cytochrome p450 isoforms.

REFERENCES

• Grose, K., et al.: Chem. Res. Toxicol., 5, 188 (1992)
• Chang, Y., et al.: Biochem. Pharmacol., 58, 825 (1992)
• Hong, C., et al.: Carcinogenesis, 23, 1297 (1992)