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6α-Hydroxy Estrone

Catalog No. H941935 Name Toronto Research Chemicals
CAS Number 1476-78-4 Website http://www.trc-canada.com
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SYNONYMS

IUPAC name
(1S,8S,10R,11S,15S)-5,8-dihydroxy-15-methyltetracyclo[8.7.0.02,7.011,15]heptadeca-2,4,6-trien-14-one
IUPAC Traditional name
(1S,8S,10R,11S,15S)-5,8-dihydroxy-15-methyltetracyclo[8.7.0.02,7.011,15]heptadeca-2,4,6-trien-14-one
Synonyms
3,6α-Dihydroxyestra-1,3,5(10)-trien-17-one
(6α)-3,6-Dihydroxyestra-1,3,5(10)-trien-17-one
6α-Hydroxyestrone

DATABASE IDS

CAS Number 1476-78-4

PROPERTIES

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DETAILS

Description (English)
The oxidative 6α-metabolite of 17β-Estradiol (E887995) and Estrone (E889050) formed by 15 selectively expressed human cytochrome p450 isoforms.

REFERENCES

  • Grose, K., et al.: Chem. Res. Toxicol., 5, 188 (1992)
  • Chang, Y., et al.: Biochem. Pharmacol., 58, 825 (1992)
  • Hong, C., et al.: Carcinogenesis, 23, 1297 (1992)