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rac 7-Hydroxy Efavirenz

Catalog No. H941820 Name Toronto Research Chemicals
CAS Number 205754-50-3 Website http://www.trc-canada.com
M. F. C14H9ClF3NO3 Telephone +1 (416) 665-9696
M. W. 331.6743696 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage -20°C Freezer Chembase ID: 170497

SYNONYMS

IUPAC name
6-chloro-4-(2-cyclopropylethynyl)-7-hydroxy-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one
IUPAC Traditional name
6-chloro-4-(2-cyclopropylethynyl)-7-hydroxy-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one
Synonyms
6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-7-hydroxy-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one

DATABASE IDS

CAS Number 205754-50-3

PROPERTIES

Certificate of Analysis Download
Apperance White to Off-White Solid
Melting Point 181-185°C
Solubility DMSO
Solubility Ethyl Acetate
Solubility Methanol
MSDS Link Download
Storage Condition -20°C Freezer

DETAILS

Description (English)
A metabolite of Efavirenz (E425000) (minor).

REFERENCES

  • Gorski, J., et al.: Biochem. Pharmacol., 47, 1643 (1994)
  • Desta, Z., et al.: J. Pharmacol. Exp. Ther., 285, 428 (1994)
  • Langmann, P., et al.: Eur. J. Med. Res., 7, 309 (1994)
  • Chang, T., et al.: Drug Metab. Dispos., 31, 7 (1994)