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N-Hydroxy-7-(4-dimethylaminobenzoyl)aminoheptanamide_Molecular_structure_CAS_251456-60-7)
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N-Hydroxy-7-(4-dimethylaminobenzoyl)aminoheptanamide

Catalog No. H941480 Name Toronto Research Chemicals
CAS Number 251456-60-7 Website http://www.trc-canada.com
M. F. C16H25N3O3 Telephone +1 (416) 665-9696
M. W. 307.388 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Chembase ID: 153871

SYNONYMS

IUPAC name
7-{[4-(dimethylamino)phenyl]formamido}-N-hydroxyheptanamide
IUPAC Traditional name
7-{[4-(dimethylamino)phenyl]formamido}-N-hydroxyheptanamide
Synonyms
4-(Dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide
M 344
M 344 (Enzyme Inhibitor)
MS 344
D 237

DATABASE IDS

CAS Number 251456-60-7

PROPERTIES

Certificate of Analysis Download
MSDS Link Download

DETAILS

Description (English)
Histone deacetylase inhibitor III. A cell-permeable amide analog of Trichostatin A that potently inhibits HDACs.

REFERENCES

  • Jung, M., et al.: J. Med. Chem., 42, 4669 (1999)
  • Ramiszewski, S.W., et al.: J. Med. Chem., 45, 753 (1999)
  • Gregoretti, I., et al.: J. Mol. Biol., 338, 17 (1999)
  • Gennadios, H., et al.: Biochemistry, 45, 7940 (1999)
  • Bottomley, M., et al.: J. Biol. Chem.,