8'-Hydroxy Dihydro Ergotamine(Mixture of Diastereomers)

• Catalog No.: H941350
• CAS Number: 90650-44-5
• M. F.: C33H37N5O6
• M. W.: 599.67678

SYNONYMS

• IUPAC name: (4R,7R)-N-[(1S,2S,4R,7S)-7-benzyl-2,10-dihydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.0^2,^6]dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0^2,^7.0^1^2,^1^6]hexadeca-1(16),9,12,14-tetraene-4-carboxamide
• IUPAC Traditional name: (4R,7R)-N-[(1S,2S,4R,7S)-7-benzyl-2,10-dihydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.0^2,^6]dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0^2,^7.0^1^2,^1^6]hexadeca-1(16),9,12,14-tetraene-4-carboxamide
• Synonyms: (5'α,10α)-9,10-Dihydro-8',12'-dihydroxy-2'-methyl-5'-(phenylmethyl)ergotaman-3',6',18-trione

DATABASE IDS

• CAS Number: 90650-44-5

DETAILS

Description (English)

The main metabolite of Dihydroergotamine, as 5-HT1A receptor agonist in the brain.

REFERENCES

• File, S., et al.: J. Neurosci., 16, 4810 (1996)
• Assie, M., et al.: Eur. J. Pharmacol., 386, 97 (1996)
• Fabre, V., et al.: Eur. J. Neurosci., 12, 2299 (1996)
• Akerman, S., et al.: Eur. J. Pharmacol., 424, 53 (1996)