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2-Hydroxyisoquinoline-1,3(2H,4H)-dione_Molecular_structure_CAS_6890-08-0)
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2-Hydroxyisoquinoline-1,3(2H,4H)-dione

Catalog No. H939800 Name Toronto Research Chemicals
CAS Number 6890-08-0 Website http://www.trc-canada.com
M. F. C9H7NO3 Telephone +1 (416) 665-9696
M. W. 177.15678 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Refrigerator Chembase ID: 170453

SYNONYMS

IUPAC name
2-hydroxy-1,2,3,4-tetrahydroisoquinoline-1,3-dione
IUPAC Traditional name
2-hydroxy-4H-isoquinoline-1,3-dione
Synonyms
2-Hydroxy-1,3(2H,4H)-isoquinolinedione

DATABASE IDS

CAS Number 6890-08-0

PROPERTIES

Certificate of Analysis Download
Apperance Brown Solid
Melting Point 197-200°C
Solubility DMSO
MSDS Link Download
Storage Condition Refrigerator

DETAILS

Description (English)
2-Hydroxyisoquinoline-1,3(2H,4H)-dione was recently discovered as a scaffold for the inhibition of HIV-1 integrase and the RNase H function of HIV-1 reverse transcriptase. It was investigated its interaction with Mg2+ and Mn2+ using different spectroscopi

REFERENCES

  • Greenwald, J., et al.: Biochemistry, 38, 8892 (1999)
  • Tramontano, E., et al.: Antiviral Res., 65, 117 (1999)
  • Schultz, S., et al.: Virus Res., 134, 86 (1999)
  • Williams, P., et al.: Bioorg. Med. Chem. Lett., 22, 6754 (1999)