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6-Hydroxy Dopamine Hydrochloride_Molecular_structure_CAS_28094-15-7)
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6-Hydroxy Dopamine Hydrochloride

Catalog No. H941730 Name Toronto Research Chemicals
CAS Number 28094-15-7 Website http://www.trc-canada.com
M. F. C8H12ClNO3 Telephone +1 (416) 665-9696
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SYNONYMS

IUPAC name
5-(2-aminoethyl)benzene-1,2,4-triol hydrochloride
IUPAC Traditional name
hydroxydopamine hydrochloride
Synonyms
Oxidopamine Hydrochloride
Topamine Hydrochloride
2,4,5-Trihydroxyphenethylamine hydrochloride
6-Hydroxydopamine Hydrochloride
5-(2-Aminoethyl)-1,2,4-benzenetriol Hydrochloride

DATABASE IDS

CAS Number 28094-15-7

PROPERTIES

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DETAILS

Description (English)
6-Hydroxydopamine is a selective catecholaminergic neurotoxin. Studies show that 6-Hydroxydopamine can be used to create an animal model of Parkinson's disease as it causes almost complete destruction of nigral dopaminergic neurons and their striatal term

REFERENCES

  • Soto-Otero, R. et al.: J. Neurochem., 74, 1605 (2000)
  • Fujita, H. et al.: Brain Res., 1113, 10 (2000)
  • Breese, G.R. et al.: 174, 313 (2000)