14β-Hydroxy 10-Deacetyl Baccatin IIIDISCONTINUED

• Catalog No.: H932500
• CAS Number: 145533-34-2
• M. F.: C29H36O11
• M. W.: 560.58954

SYNONYMS

• IUPAC name: (1R,2S,3R,4S,7R,9S,10S,12R,15R,16S)-4-(acetyloxy)-1,9,12,15,16-pentahydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0^3,^1^0.0^4,^7]heptadec-13-en-2-yl benzoate
• IUPAC Traditional name: (1R,2S,3R,4S,7R,9S,10S,12R,15R,16S)-4-(acetyloxy)-1,9,12,15,16-pentahydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0^3,^1^0.0^4,^7]heptadec-13-en-2-yl benzoate
• Synonyms: 10-Deacetyl-14β-hydroxybaccatin III; (2aR,4S,4aS,6R,9R,10S,11R,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,10,11-pentahydroxy-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one; 4β-Hydroxy-10-DAB; 14β-Hydroxy-10-desacetylbaccatin III; 14β-Hydroxy-10-deacetylbaccatin III; 14β-Hydroxydeacetylbaccatin III

DATABASE IDS

• CAS Number: 145533-34-2

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 218-220°C (dec.)
• Solubility: DMSO
• Solubility: Methanol

DETAILS

Description (English)

14β-Hydroxy 10-Deacetyl Baccatin III is a novel derivative of 10-Deacetylbaccatin III (D198250) with antitumor and antimitotic activity.

REFERENCES

• Barboni, L., et al.: Bioorg. Med. Chem. Lett., 16, 5389 (2006)