trans-3'-Hydroxy Cotinine N-β-D-Glucuronide

• Catalog No.: H924530
• CAS Number: 146275-18-5
• M. F.: C16H20N2O8
• M. W.: 368.3386
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: 1-[(2S,3S,4R,5R,6R)-6-carboxylato-3,4,5-trihydroxyoxan-2-yl]-3-[(2S,4R)-4-hydroxy-1-methyl-5-oxopyrrolidin-2-yl]-1λ^5-pyridin-1-ylium
• IUPAC Traditional name: 1-[(2S,3S,4R,5R,6R)-6-carboxylato-3,4,5-trihydroxyoxan-2-yl]-3-[(2S,4R)-4-hydroxy-1-methyl-5-oxopyrrolidin-2-yl]-1λ^5-pyridin-1-ylium
• Synonyms: 1-β-D-Glucopyranuronosyl-3-[(2S,4R)-4-hydroxy-1-methyl-5-oxo-2-pyrrolidinyl]pyridinium Inner Salt; trans-3'-Hydroxycotinine-N-glucuronide

DATABASE IDS

• CAS Number: 146275-18-5

PROPERTIES

• Apperance: White to Off-White Solid
• Melting Point: >180°C (dec.)
• Solubility: Water
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

It is a major metabolite of Nicotine in humans. Carcinogen.

REFERENCES

• Byrd, G., et al.: Drug Metab. Dispos., 20, 192 (1992)
• Benowitz, N., et al.: Br. J. Clin. Pharmacol., 51, 53 (1992)
• Hanioka, N., et al.: Xenobiotica, 31, 687 (1992)
• Ethell, B., et al.: Biochem. Pharmacol., 65, 1441 (1992)
• Yamanaka, H., et al.: Eur. J.