22-Hydroxy Cholesterol-d11(Mixture of Diastereomers)

• Catalog No.: H918012
• M. F.: C27H46O2
• M. W.: 402.65294

SYNONYMS

• IUPAC name: (1S,2R,5S,10S,11S,14R,15S)-14-[(2S)-3-hydroxy-6-(^2H₃)methyl(4,4,5,5,6,7,7,7-^2H₈)heptan-2-yl]-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-7-en-5-ol
• IUPAC Traditional name: (1S,2R,5S,10S,11S,14R,15S)-14-[(2S)-3-hydroxy-6-(^2H₃)methyl(4,4,5,5,6,7,7,7-^2H₈)heptan-2-yl]-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-7-en-5-ol
• Synonyms: Cholest-5-ene-3β,22-diol-d11; (3β)-Cholest-5-ene-3,22-diol-d11

DETAILS

Description (English)

A labelled metabolite of Cholesterol (C432501). 22-Hydroxycholesterol inhibits chemokine receptor activity.

REFERENCES

• Samson, M., et al.: J. Biol. Chem., 272, 24934 (1997)
• Mackay, C., et al.: Nature Immunol., 2, 95 (1997)
• Navenot, J., et al.: J. Mol. Biol., 313, 1181 (1997)