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22-Hydroxy Cholesterol(Mixture of Diastereomers)_Molecular_structure_CAS_17711-16-9)
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22-Hydroxy Cholesterol(Mixture of Diastereomers)

Catalog No. H918010 Name Toronto Research Chemicals
CAS Number 17711-16-9 Website http://www.trc-canada.com
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SYNONYMS

IUPAC name
(1S,2R,5S,10S,11S,14R,15S)-14-[(2S)-3-hydroxy-6-methylheptan-2-yl]-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadec-7-en-5-ol
IUPAC Traditional name
22-hydroxycholesterol
Synonyms
Cholest-5-ene-3β,22-diol
(3β)-Cholest-5-ene-3,22-diol

DATABASE IDS

CAS Number 17711-16-9

PROPERTIES

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DETAILS

Description (English)
A metabolite of Cholesterol (C432501). 22-Hydroxycholesterol inhibits chemokine receptor activity.

REFERENCES

  • Samson, M., et al.: J. Biol. Chem., 272, 24934 (1997)
  • Mackay, C., et al.: Nature Immunol., 2, 95 (1997)
  • Navenot, J., et al.: J. Mol. Biol., 313, 1181 (1997)