Home > Compound List > Product Information
4β-Hydroxy Cholesterol-d7_Molecular_structure_CAS_1246302-80-6)
Click picture or here to close

4β-Hydroxy Cholesterol-d7

Catalog No. H917982 Name Toronto Research Chemicals
CAS Number 1246302-80-6 Website http://www.trc-canada.com
M. F. C27H46O2 Telephone +1 (416) 665-9696
M. W. 402.65294 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Refrigerator Chembase ID: 170340

SYNONYMS

IUPAC name
(1S,2R,5S,6R,10S,11S,14R,15R)-2,15-dimethyl-14-[(2R)-6-(2H3)methyl(6,7,7,7-2H4)heptan-2-yl]tetracyclo[8.7.0.02,7.011,15]heptadec-7-ene-5,6-diol
IUPAC Traditional name
4β-hydroxy-cholesterol(d7)
Synonyms
3β,4β-Dihydroxycholest-5-ene-d7
cis-5-Cholestene-3,4-diol-d7
(3β,4β)-Cholest-5-ene-3,4-diol-d7
cis-3,4-Dihydroxy-5-cholestene-d7
Cholest-5-ene-3β,4β-diol-d7

DATABASE IDS

CAS Number 1246302-80-6

PROPERTIES

Certificate of Analysis Download
Apperance White Solid
Melting Point 154-159°C
Solubility Chloroform
Solubility Ethyl Acetate
MSDS Link Download
Storage Condition Refrigerator

DETAILS

Description (English)
4β-Hydroxy Cholesterol-d7 is a labelled metabolite of Cholesterol. It is formed from Cholesterol by the drug-metabolizing enzyme cytochrome P 450 3A4. A potential ligand for the nuclear receptor LXR and also a new endogenous CYP3A marker.

REFERENCES

  • Breuer, O., et al.: J. Lipid Res., 36, 2275 (1995)
  • Pikuleva, I., et al.: J. Biol. Chem., 273, 18153 (1995)
  • Chawla, A., et al.: Science, 294, 1866 (1995)
  • Bodin, K., et al.: J. Biol. Chem., 276, 38685 (1995)