17α-Hydroxy-21-chloro-9β,11β-epoxy-16α-methylpregna-1,4-diene-3,20-dione

• Catalog No.: H915450
• M. F.: C22H27ClO4
• M. W.: 390.90038

SYNONYMS

• IUPAC name: (2R,4S,5R,6R,7R,9S,18R)-6-(2-chloroacetyl)-6-hydroxy-5,7,18-trimethyl-3-oxapentacyclo[8.8.0.0^2,^4.0^5,^9.0^1^3,^1^8]octadeca-13,16-dien-15-one
• IUPAC Traditional name: (2R,4S,5R,6R,7R,9S,18R)-6-(2-chloroacetyl)-6-hydroxy-5,7,18-trimethyl-3-oxapentacyclo[8.8.0.0^2,^4.0^5,^9.0^1^3,^1^8]octadeca-13,16-dien-15-one

PROPERTIES

• Apperance: White Solid
• Solubility: Acetone
• Solubility: Chloroform
• Solubility: Dichloromethane
• Solubility: Ethyl Acetate

DETAILS

Description (English)

An intermediate in the synthesis of deuterated Mometason Furoate, a topical corticosteroid intermediate of used as an anti-inflammatory.

REFERENCES

• Shapiro, E.L., et al.: J. Med. Chem., 30, 1581 (1987)
• Graft, D., et al.: J. Allergy Clin. Immunol., 98, 724 (1996)